Intravascular hemolysis in phenol poisoning: An unforeseen and rare complication

نویسندگان

چکیده

The black phenyl is a powerful germ killer used for homes, hospitals, which easily accessible and can be consumed with the intention of self harm. Cases intravascular hemolysis through inhalation or spillage has been reported, but following ingestion rarely reported. A 25 year old previously healthy male presented after alleged was asymptomatic at presentation. By day 4, he developed fever, icterus, tachycardia, fatigue dark brown urine. Labs were Hgb 3.6g/dl, platelet count 2.75 lakhs/ul, creatinine 1.1mg/ dI, AST 244U/L, ALT 69U/L, Total Bilirubin 4.65g/dl (Indirect 3.35) PT 14.6, INR 1.23. Day 6, urine color darkened, suggestive ongoing LDH level 3614 U/L. Over full hospital stay, output maintained, didn't develop acute kidney injury. 9, patient's symptoms improved & discharged on 12. These compounds interfere oxidative phosphorylation in cells, making red blood cells losing osmotic equilibrium. This metabolic handicap may lead to premature cell lysis. Though presentation, patient serious hemoglobinuria by 4. suggests need admission patients, constant monitoring anticipate toxic potentials compound. dearth enough literature this rare complication made us report first case from North East India.

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ژورنال

عنوان ژورنال: IP international journal of forensic medicine and toxicological sciences

سال: 2023

ISSN: ['2456-9615', '2581-9844']

DOI: https://doi.org/10.18231/j.ijfmts.2023.006